yloH [2019-07-05 12:42:30]

omega subunit of RNA polymerase

Locus: BSU15690

Isoelectric point: 5.51

Molecular weight: 7.62 kDa

Protein length: 67 aa

Gene length: 204 bp

Function: unknown

Product: omega subunit of RNA polymerase

Essential: no

E.C.: 2.7.7.6

Synonyms: rpoZ

Genomic Context

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Categories containing this gene/protein

• Information processing → RNA synthesis and degradation → Transcription → RNA polymerase

Gene

Coordinates: 1,642,567 1,642,770

The protein

Catalyzed reaction/ biological activity

• Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) (according to Swiss-Prot)

Protein family

• RNA polymerase subunit omega family (according to Swiss-Prot)

Structure

• 5UH5 (transcription initiation complex from Mycobacterium tuberculosis, 37% identity, aa 1- 52) PubMed

Localization

• closely associated with RNA polymerase involved in transcribing both mRNA and rRNA operons PubMed

Expression and Regulation

Operons

• Genes: yloC-remA-gmk-yloH

  Description

  • PubMed

  Sigma factors

  • SigF: sigma factor, PubMed, in SigF regulon

  Regulation

  • expressed during vegetative growth and early during sporulation in the forespore (SigF) PubMed

• Genes: yloC-remA-gmk-yloH-yloI-priA-defA-fmt-yloM-yloN

  Description

  • PubMed

• Genes: yloB-yloC-remA-gmk-yloH

  Description

  • PubMed

  Regulation

  • expressed during sporulation in the mother cell PubMed

Biological materials

Mutant

• BKE15690 (yloH::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_ATCAATTGACGGATCTAACA, downstream forward: _UP4_TAGTAGCACAAGTAGCAACC
• BKK15690 (yloH::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_ATCAATTGACGGATCTAACA, downstream forward: _UP4_TAGTAGCACAAGTAGCAACC

References

Reviews

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Original publications

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